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Ohio Eminent Scholar Professor
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| (614) 247-8847 paulaitis@chbmeng.ohio-state.edu |
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| Research Interests |
| Molecular simulations and modeling of weak protein-protein interactions; the role of hydration in biological organization and self-assembly phenomena; multiscale modeling of biological interactions. |
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| Education |
| B.S.,Pinceton University, 1968
M.S., Stanford University, 1970
Ph.D., University of Illinois, 1976
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| Honors |
Ohio Eminent Scholar, 2005
Member, Academy of Sciences of Technological Cybernetics of Ukraine, 1994
Presidential Young Investigators Award, 1984
Alexander von Humboldt Fello, 1983
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-Michael Paulaitis |
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Recent Publications
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- Paliwal, A., D. Asthagiri, D. Abras, A. M. Lenhoff and M. E. Paulaitis, “Light scattering studies of protein solutions: Role of hydration in weak protein-protein interactions,” Biophys. J. submitted (2005).
- Asthagiri, D., A. Paliwal, D. Abras, A. M. Lenhoff and M. E. Paulaitis, “A consistent experimental and modeling approach to light scattering studies of protein-protein interactions in solution,” Biophys. J. 88 (2005).
- Ashbaugh, H. S., L. R. Pratt, M. E. Paulaitis, J. Clohecy and T. L. Beck, “Deblurred Observation of the Molecular Structure of an Oil-Water Interface,” J. Am. Chem. Soc. 127, 2808 (2005).
- Paliwal, A., D. Asthagiri, D. P. Bossev and M. E. Paulaitis, “Pressure Denaturation of Staphylococcal Nuclease Studied by Neutron Small-Angle Scattering and Molecular Simulation,” Biophys. J.87, 3479 (2004).
- Weathers, E. A., M. E. Paulaitis, T. B. Woolf and J. H. Hoh, “Reduced amino acid alphabet is sufficient to accurately recognize intrinsically disordered protein,” FEBS Letters576, 348 (2004).
- Asthagiri, D., L. R. Pratt, M. E. Paulaitis and S. B. Rempe, “Hydration structure and free energy of biomolecularly specific aqueous dications, including Zn + and first-transition-row metals,” J. Am. Chem. Soc.126, 1585 (2004).
- Paulaitis, M. E. and L. R. Pratt, “Hydration Theory for Molecular Biophysics,” Adv. in Protein Chemistry62, 283 (2002).
- Kumar, S., Xinghua, Y., Trapp, B. D., J. H. Hoh, and M. E. Paulaitis, “Relating interactions between neurofilaments to the structure of axonal neurofilament distributions through polymer brush models,” Biophys. J. 82, 2360 (2002).
- Kumar, S., Xinghua, Y., Trapp, B. D., Paulaitis, M. E., and J. H. Hoh, “Analysis and simulation of neurofilament distributions: implications for mechanisms of interfilament spacing,” J. Neurosci. Res. 68, 681 (2002).
- Ashbaugh, H. S. and M. E. Paulaitis, "Effect of Solute Size and Solute-Water Attractive Interactions on Hydration Water Structure Around Hydrophobic Solutes,” J. Am. Chem. Soc.123, 10721 (2001).
- Hummer, G., Garde, S., García, A. E., Paulaitis, M. E., and L. R. Pratt, “Hydrophobic Effects on a Molecular Scale,” J. Phys. Chem. B 102, 10 469 (1998).
- Hummer, G., Garde, S., García, A. E., Paulaitis, M. E., and L. R. Pratt, “The pressure dependence of hydrophobic interactions is consistent with the observed pressure denaturation of proteins,” Proc. Nat. Acad. Sci.95, 1552 (1998).
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